3d Signatures

Here is a disruptive diagnostic company in the personalized medicine space called 3D Signature that I think many of you might be interested in. Its technology could save lives and determine how cancer will progress and what are the best modes of treatment for each individual patient.  www.3dsignatures.com

This short video explains the science behind the company’s proprietary software that can analyze a patient’s chromosomal arrangement – or signature – through a simple non-invasive blood test or tissue sample. www.youtube.com/watch?v=OntyoBmXO04

The global cancer diagnostics market is expected to reach $13.1 Billion by 2020. Unlike most diagnostic companies, 3D Signatures’ proprietary imaging software goes beyond identifying whether a patient suffers from a specific disease or condition. Its platform tells doctors how to personalize treatment for patients and analyzes a specific part of an individual’s unique DNA (their telomeres) to determine how a disease will progress and if and how they will respond to treatment.


Parkinson Disease

The American Parkinson Disease Association (APDA) announces today a collaboration with Smart Patients, an online support site for patients and caregivers, to create a new Parkinson’s disease (PD) community where people impacted by PD can join the community for free to share, interact, and learn from each other in a safe, supportive environment. This network extends APDA’s resources to help those affected by PD no matter where they are located to live life to the fullest and connect to others who have extensive experience with the disease.

We are thrilled with our partnership with Smart Patients to launch this community. This network is designed for people with PD, care partners, and family members,” explains Robin Kornhaber, APDA Vice President of Programs and Patient Services. “This innovative opportunity will further a dialogue to nurture the PD community, provide socialization, education, and critical access to information – and will allow us to expand our reach across the country.”

Smart Patients believes that patients and caregivers are the most underutilized resource in medicine. By partnering with Smart Patients, APDA is empowering people with Parkinson’s to improve care for themselves and others.

We are proud to work with the APDA to connect people with Parkinson’s with one another. Community can provide peace of mind through social and emotional support, not to mention those practical tips patients and families learn through direct experience,” said Roni Zeiger, MD, CEO of Smart Patients.

The PD community is invited to visit the site through the following two links: https://www.apdaparkinson.org/resources-support/smart-patients/  or www.smartpatients.com/apda. Individuals can join the community by sharing their email address and setting up a free personal account. Once the account is confirmed participants will have access to information, resources, and be able to participate in community conversations on topics of interest.

Parkinson’s disease is a progressive neurological disorder affecting more than one million people in the United States. Approximately 60,000 people are newly diagnosed each year. Onset commonly occurs after the age of 60, however up to ten percent will receive a diagnosis before the age of 50. Parkinson’s is characterized by motor problems including slowness of movement, rigidity, and tremor with balance and gait problems sometimes occurring later in the course of illness. Some people may also experience a decrease in facial expression, low voice volume, small handwriting, and difficulty with fine motor movements. A number of non-motor symptoms are associated with Parkinson’s, including fatigue, anxiety, depression, and sleep disturbance. It is important to understand that symptoms vary from person to person.

Contact: Stephanie Paul | 800-223-2732 | SPaul@apdaparkinson.org | www.apdaparkinson.org

About the American Parkinson Disease Association:
The American Parkinson Disease Association (APDA) is the largest grassroots network dedicated to fighting Parkinson’s disease (PD) and works tirelessly to assist the more than 1 million Americans with PD  live life to the fullest in the face of this chronic, neurological disorder. Founded in 1961, APDA has raised and invested more than $170 million to provide outstanding patient services and educational programs, elevate public awareness about the disease, and support research designed to unlock the mysteries of PD and ultimately put an end to this disease. To join us in the fight against Parkinson’s disease and to learn more about the support APDA provides nationally through our network of Chapters and Information & Referral (I&R) Centers, as well as our national Research Program and Centers for Advanced Research, please visit us at www.apdaparkinson.org

About Smart Patients:
Smart Patients is an online community where patients and their families affected by a variety of illnesses learn from each other about treatments, challenges, and how it all fits into the context of their experience. While providing patients with safe and high quality peer support, we help the healthcare system learn from patients in order to serve them bette

Walking Red On Demand Mobile Salon & Fitness Service.

Have a big date coming up and don’t have time to go to the hair salon, the nail salon, the spa to get a massage or the gym to get your daily workout in while on vacation?  Well, never fear, Walking Red is here.

WalkingRed.com makes it easier than ever to feel like a celebrity while traveling!  WalkingRed is the premier on demand mobile beauty and fitness service created to provide customers the star treatment at their convenience.

Currently available in the UK (soon expanding to additional cities and countries), WalkingRed is equipped with a leading team of beauty and fitness professionals providing a variety of services across the industry. Every WalkingRed artist is fully qualified, insured and complies with high service standards.  Each are screened and certified in person, are required to pass CRB checks, and must be fully insured.

The End of Vaccines??

“Immunonutrition over vaccination” is the conclusion of a landmark study published by The Knowledge of Health, a California based health watchdog group which is calling for a major re-direction in the way infectious disease is prevented. The 85-page white paper explores less problematic ways to address infectious diseases aside from vaccines at a time when they are under increased scrutiny

The report claims there is massive over-vaccination of human populations as most well nourished unvaccinated Americans naturally produce their own antibodies and experience only transient minor symptoms or are asymptomatic when exposed to common pathogens such as measles, chicken pox, poliovirus or whooping cough.   For example, only 1 in 200 to 1 in 1000 people experience paralysis when exposed to poliovirus and most don’t even know they naturally developed antibodies on their own without vaccines.  Modern medicine mistakenly calls this herd immunity.

The report argues that immunonutrition consisting of zinc therapy to activate T-memory cells made in the thymus gland to produce a symptomless response to infectious bacteria or viruses whether they be from vaccines or from natural exposure, is the best way to treat illnesses. The report notes that the two age groups that do not respond well to vaccines, the very young and the very old, have impaired immunity due to a deficiency of zinc.  The report calls for universal food fortification and dietary supplementation prior to vaccination.  The report claims the only way vaccines can be improved and side effects and vaccine-induced infection avoided is to employ immunotherapy.

The full report is available at http://beyondvaccines.com

American Parkinsons m Social Media Campaign

  April is Parkinson’s Disease Awareness Month and the American Parkinson Disease Association (APDA) is proud to launch today a new social media campaign entitled unshakeable spirit that will help bring much needed attention not only to the disease itself, but to showcase what life is like for those impacted by Parkinson’s disease (PD) and how you can live a full and optimistic life despite a PD diagnosis. User-generated content featuring photos and inspiring captions created using APDA’s “frame generator” will authentically capture and highlight important moments and attitudes that depict this unshakeable spirit.

Every nine minutes there is a new diagnosis of PD, which means that in April alone nearly 5,000 individuals in this country will learn they have the disease. PD is a chronic, progressive disease with no treatment, therapy, or drug to slow or halt its progression. However, with the proper medical care, support system, education and services, many people with PD can live a full and active life. APDA is here to help connect people with the care and services they need.

Starting today April 11, which is World Parkinson’s Day, APDA’s new unshakeable spirit campaign shines a light on the people and the stories of the PD community. This multi-phase campaign features stories and faces that are meant to inspire, educate and help people know they are not alone in their PD journey will be featured on the APDA Facebook page and via Twitter.  All those impacted by PD, including people living with the disease, their care partners, medical professionals and others are welcomed to participate, not only in April but all throughout the year as this campaign will carry on beyond PD Awareness Month.

“At APDA, our unshakeable spirit comes from a belief that as a community, we will solve the riddle of Parkinson’s disease. We are inspired by the amazing individuals with PD and their families who participate in hundreds of clinical trials and health and wellness programs every day – both quietly and boldly. APDA is there for them all along the way, and we are both proud and excited to start this unshakeable movement,” states APDA President and CEO, Leslie A. Chambers.

To get involved, people can go to a dedicated landing pageapdaparkinson.org/unshakeablespirit – developed specifically for the unshakeable spirit campaign where they can generate their own “frame”.  The “frame generator” will allow people to upload a personal photo, choose an inspiring theme, tell their PD story and share it with their friends, family, and the world if they choose. The images below are examples of what a finished frame looks like.

The campaign was conceived by marketing partner teamDigital; a digital and social agency located in the greater New York area. “As someone who is living with Parkinson’s, and as a member of an APDA support group, I am so proud to be supporting the mission of this incredible organization,” said teamDigital CEO Jeff Butchen. “APDA is an unshakeable force in the lives of so many, and we at teamDigital are grateful for the opportunity to amplify the work they do nationwide.”

“We all want to live life to the fullest, but for people with PD it might take a little more to get there. A little more drive, a little more optimism and a little more support – and that’s the essence of the unshakeable spirit campaign. We know these personal stories and images will help further strengthen the PD community – inspiring them and showing them that there are others out there who know what they’re going through. We look forward to collecting and sharing a tremendous number of photos and stories not only in April, but all year long,” states Chambers.

For more information about unshakeable spirit campaign, or about the American Parkinson Disease Association, please visit www.apdaparkinson.org.

About the American Parkinson Disease Association:  The American Parkinson Disease Association (APDA) is the largest grassroots network dedicated to fighting Parkinson’s disease (PD) and works tirelessly to assist the more than 1 million Americans with PD live life to the fullest in the face of this chronic, neurological disorder. Founded in 1961, APDA has raised and invested more than $170 million to provide outstanding patient services and educational programs, elevate public awareness about the disease, and support research designed to unlock the mysteries of PD and ultimately put an end to this disease. To join us in the fight against Parkinson’s disease and to learn more about the support APDA provides nationally through our network of Chapters and Information & Referral (I&R) Centers, as well as our national Research Program and Centers for Advanced Research, please visit us at www.apdaparkinson.org.

About teamDigital:  For over 20 years, teamDigital has led break-through programs to engage consumers and activate brands. In addition to strategic planning and program planning, we provide full support services from administrative/legal services to backend technical development. Visit http://teamdigital.com for more information.

Stem Cells and Seizures

Texas A&M research that shows tiny vesicles from adult mesenchymal stem cells, administered nasally, can limit damage to the brain caused by seizures. The research just published (at 3pm EDT today) in the Proceedings of the National Academy of Sciences.

Let me know if you might need a PDF of the study, or are interested in speaking with our researchers.



Holly Shive | Public Relations Director

Governmental & Public Affairs, Health Science Center | Texas A&M University

Mail Stop 1359 | 8441 Riverside Pkwy, Clinical Building 1, 3rd Floor | Bryan, TX 77807

ph: 979.436.0613 | hshive@tamhsc.edu

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News Release

Texas A&M research points to potential way to prevent seizure-caused brain damage

(BRYAN, Texas) — Tiny vesicles isolated from adult mesenchymal stem cells and administered intranasally can limit the damage to the brain of animal models caused by a seizure disorder called status epilepticus, according to research published today in the Proceedings of the National Academy of Sciences (PNAS).

Status epilepticus is the formal name for a single seizure lasting longer than 30 minutes or a series of seizures in which the person doesn’t regain consciousness in between them. If it is not quickly stopped, even one episode can cause brain damage, loss of cognitive function and memory loss.

“Saving the brain from injury and disease is certainly one of the holy grails of medicine,” said Darwin J. Prockop, MD, PhD, the Stearman Chair in Genomic Medicine, professor at the Texas A&M College of Medicine and co-senior author of the article. “Our paper suggests one way that this might be done, and not by a procedure that requires brain surgery or even injection into a vein: All that would be required is a nasal spray that a patient might receive in a doctor’s office.”

The compound in the nasal spray is anti-inflammatory exosomes, or extracellular vesicles, which Prockop and his team isolated from cultures of mesenchymal stem cells, a type of adult stem cell.

Ashok K. Shetty, PhD, a professor at the Department of Molecular and Cellular Medicine at the Texas A&M College of Medicine, associate director of the Institute for Regenerative Medicine, research career scientist at the Olin E. Teague Veterans Medical Center and co-senior author of the paper, and his team tested the efficiency of these exosomes in a status epilepticus model with damage from a period of acute seizures. “What is remarkable is that the animal models were rescued from long-term effects of the seizure-induced brain injury by a nasal spray of exosomes,” Prockop said. It was able to ease inflammation of the neurons, prevent cognitive and memory dysfunction and stop abnormal neurogenesis in the hippocampus, a vital part of the brain responsible for memory.

“We gave the intranasal vesicle spray twice over 24 hours, the first one at two hours after the onset of a status epilepticus episode, and such treatment was effective at reducing multiple adverse effects on the hippocampus,” said Shetty. “In fact, the vesicles were able to move to the hippocampus in six hours, and their neuroprotection was enough to prevent loss of normal cognitive and memory function as well as abnormal neurogenesis, one of the substrates involved in formation of new memories.”

Drugs like benzodiazepines, which are tranquilizers, and hydantoins, a type of anticonvulsant, are used to stop status epilepticus episodes, but they are often unavailable—especially if the person hadn’t previously been diagnosed with epilepsy, which is the case 75 percent of the time—and they are ineffective perhaps as much as 30 percent of the time. “There really hasn’t been anything noninvasive like this to stop the cascade of inflammation and abnormal neuronal wiring or epileptogenesis that occurs after a status epilepticus event,” Shetty said. “These vesicles do seem able to protect the brain after seizures, stop neuroinflammation and prevent the development of chronic epilepsy that often results without this treatment.”

Although the findings are promising, the researchers urge caution before jumping to conclusions about a treatment for humans with seizures.

“Before this therapy can safely be tested in patients, we need to do great deal of further work,” said Prockop, who is also the director of the Texas A&M College of Medicine Institute for Regenerative Medicine. “But the inflammation in the brain caused by acute seizures is similar to the inflammation seen in the late stages of other brain diseases, including Alzheimer’s disease, parkinsonism, multiple sclerosis and traumatic injuries,” Shetty added. “Therefore, the promise of this new therapy is enormous.”

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Brain Health

I found this article to be interesting so I thought that I would share it with all of you.

Sorry I haven’t posted in so long. I have had bronchitis, I have fell twice, and now I have pneumonia! I am going to do my best to post a lot more.

Prominent African American Advocate Calls Brain Health the greatest 21st Century Civil Rights Issue

Author Dan Gasby joins American Brain Foundation Board to Raise Awareness of Racial Disparities in Diagnosis and Research

Minneapolis, MN (January 16, 2017)—As our country celebrates the remarkable life and legacy of the late Martin Luther King Jr., today author and advocate Dan Gasby is joining forces with the American Brain Foundation (ABF) to raise awareness of the tremendous racial disparities that exist between African Americans and non-Hispanic whites when it comes to the diagnosis, treatment and lack of adequate studies of brain disease.

Brain Health is the greatest 21st Century civil rights issue,” said Gasby. “When you lose your cognitive ability, your rights as a human being are greatly diminished.”

Gasby says this is particularly devastating for African Americans, who are twice as likely as non-Hispanic whites to develop late onset Alzheimer’s and less likely to have a diagnosis of their condition, which often results in little time for treatment and planning. Gasby’s wife, B. Smith, a nationally recognized celebrity chef, supermodel and lifestyle maven, was diagnosed with Alzheimer’s disease in 2013.

From my experience as a caregiver, I know that brain disease robs sufferers of their dreams and ambitions and of their hopes and even their homes,” said Gasby, who co-authored the moving memoir, “Before I Forget” with his wife. “Our brain health is often directly tied to our socioeconomic status. We need more funding, more awareness and more compassion for the more than 50 million Americans afflicted with brain diseases.”

Kevin Goodno, Board Chair of the ABF, a national charity whose mission is to bring researchers and donors together to defeat brain disease, said Gasby’s election to the Board continues to diversify the organization and better positions the ABF to address the critical need for funding to accelerate research.

Each of our Board members shares our organization’s collective passion to find a cure,” Goodno said. “Throughout our history, the American public has successfully rallied to beat back pervasive threats to our personal and public health, such as polio, cancer and HIV/AIDS. It’s now time to defeat brain disease.”

Gasby joins a distinguished ABF Board that includes world-renowned neurologists, a former NFL Super Bowl champion, Vice President Walter Mondale (Honorary Chair) and the most recent new member Susan Schneider Williams, artist and widow of late actor and comedian Robin Williams.

For more information about the American Brain Foundation or to learn more, visit www. AmericanBrainFoundation.org, or find the Foundation on Facebook, Twitter, Google+ and YouTube.